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My experience with metformin has been awesome. I have been using this medicine for about a year now and have has great results. I know have regular periods which is great because I used to get it every 15 days or miss months here and there. Another fantastic thing is that I can now function when I am menstruating which used to be impossible for me due to the horrible pain. I now have manageable pain and don't have to get shots for it. I've also been able to lose 77 lbs that I had gained. Overall I've had a wonderful experience with this medication. I believe that taking my doctor's advice was the best thing I ever did, I think the combination of the medicine, changed eating habits and exercise all helped.

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Morning blood sugar ranges between 115-128 I take 500 mg of metformin once a day.

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INVOKAMET (canagliflozin and metformin hydrochloride) combines two oral antihyperglycemic agents with complementary mechanisms of action to improve glycemic control in patients with type 2 diabetes: canagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, and metformin hydrochloride, a member of the biguanide class.

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The combinations of metformin and rosiglitazone (Avandamet), metformin and pioglitazone (Actoplus Met), metformin and sitagliptin (Janumet), and metformin and repaglinide (PrandiMet), however, are still sold only as brand-name products.

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Up to 30% of adults older than age 50 have difficulty absorbing vitamin B12 in the digestive tract due to decreased levels of hydrochloric acid, so taking an oral B12 supplement would be of little use in this situation (this is a reason that many older adults get B12 injections).

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Akkermansia genus abundances adjusted to match the scale of the metformin effect on Escherichia genus abundance reported here (metformin-treated samples were roughly 150% as likely to have non-zero abundance, with a roughly threefold higher abundance where present), while retaining their data set origin labels.

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That makes sense, because all of the epidemiologic data suggesting a cancer benefit came from studies that used those doses, said Michael Pollak, MD, of McGill University in Montreal, who has extensively studied metformin and its anticancer potential.

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No one thought we could limit mutations before, but perhaps metformin can do it.

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Patients with newly diagnosed type 2 diabetes had similar improvement in glycemic control whether treated with acarbose (Precose) or metformin, investigators in a randomized trial reported.

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If you try metformin and find the side effects overwhelming after a month's trial--typical problems would be dramatic digestive problems or a feeling of exhaustion and low grade toxicity--talk to your pharmacist about trying another brand or move your prescription to another pharmacy that carries another brand.

We designed the Metformin in Gestational Diabetes Trial to rule out a 33% increase in a composite of perinatal complications in infants of women treated with metformin as compared with insulin.

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The test was ended when the participant could no longer continue.

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Overall, subjects receiving either berberine or metformin had significant improvement in measures of insulin sensitivity compared to placebo.

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The current study is unique in that it focused on continuous exercise at several submaximal intensities that are relevant to activity patterns of people with type 2 diabetes and that we examined the interaction between exercise and metformin on the glycemic and hormonal responses to a subsequent meal.

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